Without having the time to fully investigate it, I have to say that the science sounds very promising, and when perfected could very well take the place of inhalers as an effective NRT device.
From what little I've read, they're still unsure about the full health risks that might be involved... but the same could be said for ecigs in general... as well as all the other NRT products containing TSNAs.
My only concerns about experimenting with this on your own is in regulating the amount of nicotine absorbed.
How many mg of pyruvic acid is vaporized at what temp?
How many mg of nicotine pyruvate is created by the reaction of that amount of pyruvic acid vapor through what mg/ml concentration of nicotine solution?
(Using a high concentration solution has it's own risks for nicotine overdose through leakage/lips/mouth lining.)
How much of the nicotine pyruvate escapes the filler material as particles?
What is the maximum amount that is going to have the potential to be absorbed at one time?
Another consideration is working with pure pyruvic acid itself.
While it is a naturally occurring chemical that has benefits to the body, once you take a chem out of it's natural state and concentration it can become dangerous.
Pure pyruvic acid is listed as a hazmat chemical that can cause severe burns and eye damage, and I've read that some form of pyruvic acid is used for facial peels.
Exactly how strong an acid and what the full risks are from working with it I can't say.
Unfortunately I don't have the kind of free time to research exciting new things that I once had anymore.
All in all it sounds really interesting for NRT advancement, but since I'm quite happy with vaping, playing with new flavors, and don't have any cravings for the ciggys anymore, when this does come to market ~2015 I won't be on the waiting list for it.
Of course, I'd be interested to see how you come along in your experiments if you feel you must.
I'd just advise taking it slow, do all your homework first, get all the answers to your/my questions, and use good safety precautions before jumping right in.